Thymidylate Synthase Proteins

Thymidylate Synthase Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed?... Thymidylate Synthase Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us... Thymidylate Synthase Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... Thymidylate Synthase Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

Thymidylate Synthase (TS) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Synonyms

HST422; MGC88736; OK/SW-cl.29; Thymidylate synthase; thymidylate synthetase; TMS; Ts; Tsase; TYMS; tysy

Filters

Less

1 result

Species

Expression System

Product Grade

Application

Price

Compare

1 result

Invitrogen

Human Thymidylate Synthase (aa 102-174) Control Fragment Recombinant Protein

Invitrogen

Human Thymidylate Synthase (aa 102-174) Control Fragment Recombinant Protein

Species

Human

Expression System

E. coli

Product Grade

Research Use Only

Application

Ctrl BLOCK

Price

Cat # RP-109441

100 µL

Custom Antibody Service

Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.

More than 18,000 custom antibodies created so far.

Talk to a specialist now

Thymidylate Synthase Proteins

Protein Information

Synonyms

Custom Antibody Service

We're here to help

Your items have has been added!